I "mustache" you to say NO to drugs!

It's National Red Ribbon Week and I am in love with my daughter's school theme for the day-  "I 'mustache' you to say NO to drugs!"  

I will be honest, I wish my school would have been as cool as my daughters and did this theme.  :)

Back to the real topic-  SAY NO TO DRUGS!  At what age do you start to talk about drugs with your kids?